Pharmacological properties
Amitraz is an acaricide from the amidine group, active against sarcoptoid mites (Otodectes spp., Psoroptes Notoedres cati) as well as Demodex spp. Amitraz acts by contact, disrupting the octopamine receptors of the ticks' nervous system, which causes paralysis and death of parasites, negatively affects the reproductive organs of female ticks, reducing egg production and their viability.
Clotrimazole is an antifungal agent from the group of imidazole derivatives with a broad spectrum of antifungal activity (Trichophyton Epidermophyton Microsporum) and weak antibacterial activity (Streptococcus spp. ). The mechanism of action of clotrimazole is to block the synthesis of nucleic acids and proteins, as well as the synthesis of ergosterol in fungal cells, which leads to damage to their cell membrane and cell death.
The drug is effective against fungal populations. mites resistant to chlorine and phosphorus insecticides. It penetrates and accumulates in the epidermis, hair follicles, fat and sweat glands and has acaricidal, anti-inflammatory and emollient properties.
Indications for use
Treatment of dogs, cats and fur animals with otodectosis , sarcoptosis, nototodrosis, demodecosis and fungal skin diseases, in the combined course of parasitic invasions and infections caused by fungal diseases.
How to use
In case of otodectosis, inject 0.2-0.5 ml of the drug , depending on the size of the animal, to both ears (even in the case of changes in only one). The initial ear canal is cleaned of scabs and crusts using a cotton swab that is moistened with the drug, in order to completely treat the ear surface, the auricle is folded lengthwise in half and lightly massaged. Treatment is carried out once a day for 3 days until the clinical symptoms of the disease disappear (3-5 treatments).
In the case of demodecosis, sarcoptosis and notetodrosis, the preparation is applied to previously cleansed affected areas of the skin from the periphery in the amount of 0.5 ml/kg body weight once a day for 2-3 days until the clinical symptoms of the disease disappear (6-8 treatments), additionally treating the skin around the affected areas with a width at least 1 cm. In the case of a large area of skin lesions, it is recommended to treat the affected areas first on one half of the animal's body, and after a day - on the other half of the body.
In the case of fungal diseases, treatment of the affected areas of the animal's skin should be carried out in a specific manner once a day for 3-5 days.
Three drops of the preparation from the dispenser bottle and 12 drops of the preparation from the dropper bottle correspond to 0.5 ml.
Contraindications
Individual sensitivity to the ingredients of the drug.
Do not use in pregnant and breastfeeding women, as well as in puppies and kittens under 2 months of age.
Note
In case of skin lesions at the treatment site, a sting is possible .
When treating animals, use polyethylene or rubber gloves.
Release form
Polymer vials with a stopper and a dropper dispenser with a capacity of 10, 15, 30 ml each.
Storage conditions< br />Dry, dark place inaccessible to children at a temperature of 5 to 25°C.
Shelf life
Shelf life - 2 years.
For use in veterinary medicine!