Recombinant canine interferon Kaniferon.
Qualitative and quantitative composition

Sterile isotonic aqueous solution of recombinant interferon, total protein <35 mcg/ml.

Pharmaceutical form

Sterile isotonic aqueous solution. Transparent, colorless, slightly opalescent liquid.

Immunobiological properties

The active ingredient in 1 ml of the drug is canine interferon alpha with an antiviral activity of 1,000,000 international units (IU), excipients: 8.00 mg sodium chloride; 1.77 mg sodium hydrogen phosphate dihydrate; 0.25 mg potassium dihydrogen phosphate; 50.0 mg dextran 40; 0.1 mg tween 20; 0.058 mg EDTA; 9.42 mg benzyl alcohol and water for injection.

The mechanism of action consists in suppressing the reproduction of DNA and RNA viruses in infected cells, increasing the resistance of healthy cells of the body to viral infection, enhancing the phagocytic activity of macrophages and increasing the specific cytotoxicity of lymphocytes.

Animal species

Dogs

Indications for use
The drug Kaniferon is used for therapeutic and prophylactic purposes in dogs with gastrointestinal, acute respiratory and other diseases of viral or mixed etiology.

Contraindications

A contraindication to the use of the drug Kaniferon is an individual increased sensitivity of the animal to interferons, severe liver damage, hypochromic anemia, autoimmune diseases.

Side effects

Not observed.

Special reservations for use

The dosage should not exceed 1.5 times the loading dose per day for a course of up to 5 days, and 0.75 times the dose for subsequent treatment. Open solution is stored for no more than 12 hours at 4-8°C.

Pregnancy and lactation precautions.

Use by pregnant and lactating dogs is contraindicated, since safety studies during pregnancy and lactation have not been conducted.

Interaction with other drugs and other forms of interaction

Do not use the drug simultaneously with drugs that have immunosuppressive properties.

Doses and route of administration for animals of all ages
The drug Kaniferon is administered intramuscularly at a therapeutic dose of 1,000,000 IU per 10 kg of body weight, which corresponds to 1.0 ml once a day. For puppies and dogs weighing less than 10 kg, the same therapeutic dose of 1,000,000 IU (1.0 ml) of the drug is used once a day. The course of treatment is 5-7 days. It is advisable to start treatment at the first symptoms of an infectious disease.

Overdose (symptoms, emergency measures, antidotes)

Some animals may experience fever, lethargy, drowsiness when given an increased dose, and the above reactions disappear after a while. In case of individual sensitivity and allergic reactions, the drug is discontinued and antihistamines are prescribed to the animal.

Withdrawal period (correction)

Not established.

Special reservations for persons and service personnel who administer animal protection products

Working with the drug does not require special safety measures. In case of accidental administration to a person, you must consult a doctor.

Main forms of incompatibility

Kaniferon cannot be mixed in the same syringe with other drugs. Joint use with immunobiological agents (serum and immunoglobulin) is allowed.

Shelf life

Shelf life - 24 months. After first opening the primary package, use within 12 hours.

Special storage precautions

Store in a dry place at a temperature of 2 0C to 8 0C.

Nature and composition of the primary packaging container

2.5 ml vials (1,000,000 IU/ml).

Name and location of the manufacturer

Vetline Agrosciens LLC, 61001 Kharkiv, Rustaveli St., 11 B.

Special safety precautions when handling unused products

Unused products or products whose expiration date has expired do not require special disposal rules.