Albendazole-250 Beef Flavored Tablets
Composition.
1 tablet (0.5 g) contains the active substance: albendazole 250 mg.
Production form
Blisters:
10 tablets of 0.5 g
Pharmacological properties
Albendazole belongs to the group of benzimidazoles that inhibit the polymerization of tubulin into microtubules, which leads to impaired absorption and intracellular transport of nutrients and metabolic substances (adenosine triphosphoric acid and glucose), as well as mitochondrial reactions by inhibiting fumarate reductase, which leads to the death of parasites.
After oral administration, albendazole is absorbed in the gastrointestinal tract.
The bioavailability of albendazole is low. The time to reach the peak concentration of albendazole sulfoxide is 2-5 hours. It binds to plasma proteins by 70%.
It is excreted in the bile as an active metabolite of albendazole sulfoxide, and only a small amount is excreted in the urine.
Application
Prevention and treatment of dogs, cats and fur animals with invasive diseases caused by
gastrointestinal nematodes: Toxocara spp;
tapeworms: Taenia solium, Dipylidium caninum, Diphyllobothrium latum;
trematodes: Opistorchis felineus.
Dosage.
Give the animal orally with food or directly.
For treatment: twice with an interval of 7-8 days at a dose of 1 tablet per 10 kg of body weight.
For preventive purposes, deworming is carried out once every 3 months.
Contraindications.
Hypersensitivity to albendazole.
Do not use in animals during pregnancy and lactation.
Storage conditions.
Store in a dry, dark place, out of reach of children, at a temperature of 2 to 30 °C and a relative humidity of no more than 75%. The product shelf life is 2 years.