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Composition
One tablet contains:
praziquantel - 50 mg;
levamisole hydrochloride - 38 mg;
ivermectin - 2 mg;
tablet-forming excipients.
Pharmacological properties
Exhibits the pharmacological properties of three components, which provides a wide spectrum of action against endo- and ectoparasites, namely:
ivermectin in nematodes, arachnids, insects and gadfly larvae enhances the connection of GABA (gamma-aminobutyric acid) with special receptors on the nerve endings of the parasite, thereby blocking the innervation of the parasite, causing its paralysis and death;
praziquantel in cestodes and trematodes inhibits muscle innervation and disrupts the membrane-permeable functions of cells, which causes their death;
levamisole inhibits the enzyme of the main metabolism fumarate reductase, blocks the formation of ATP, disrupts the metabolism of glucides, paralyzes nerve nodes, which causes paralysis and death of nematodes already in the first 12-24 hours after administration.
Indications
Prevention and treatment of diseases caused by skin parasites: fleas, lice, ixodid and scabies mites; larvae and adult nematodes, cestodes and some trematodes, namely; ancylostomiasis (pathogen Ancylostoma caninum), dipylidiosis (Dipylidium caninum), diphyllobothriasis (Diphyllobothrium latum, D. minus), toxocariasis (Toxocara canis, T. cati), toxascariasis (Toxascaris leonina), trichuriasis (Trichoceptalus vulpis ma T.nutpia), taeniasis (Taenia hydatigena, T. multiceps), uncinariosis (Uncinaria stenocephala), opisthorchiasis (Opisthorchis tenuicolis, O.viverrini, O. sinensis), paragonimiasis (Paragonimus westermani), mesocestoidiasis (Mesocestoides linattus, M litteratus, M.corti, M.petrovi), dirofilariasis (Dirofilaria immitis, D. renens), echinococcosis (Echinococcus granulosus ma E. multilocularis) (only sexually mature forms) and some other parasites of dogs.
Doses and method of administration
Dogs - 1 tablet per 10 kg of body weight. The tablets are crushed and mixed with 1/3 of the feed mass of the morning ration. For young animals (up to 1.5 years old), the specified dose is divided into 2 parts and fed at intervals of one day. In the presence of demodicosis, the drug is administered again 10-12 days before. At the same time, drugs for symptomatic therapy are used.
If animals do not have skin parasites, then Brovanol should be used for preventive deworming.
Contraindications
Do not use for sheltie, collie, bobtail dogs and puppies under 6 months of age.
Precautions
Do not exceed the specified doses. Use the drug only on the recommendation of a veterinarian.
Storage
Dry, dark place at a temperature from +1°C to +25°C.
Shelf life - 3 years.