🐕 CEFTRIAXONE 🐈
🚑 Treatment of respiratory diseases, urogenital system, skin, soft tissue and bones, otitis, sepsis, meningitis caused by microorganisms sensitive to ceftriaxone in dogs and cats; prevention of postoperative complications.
Dosage:
⚠ Store the prepared solution for no longer than 6 hours at a temperature not higher than 25 ° C and no longer than 24 hours at a temperature of 2 to 8 ° C.
The drug is administered intramuscularly or intravenously once a day.
🐕 For intramuscular administration to dogs, the contents of one bottle (1.0 g of the drug) are dissolved in 3.6 ml of 1% lidocaine solution or 0.25%-0.5% novocaine solution or sterile water for injection. 1 ml of the prepared solution contains approximately 250 mg of ceftriaxone.
🐈 For intramuscular administration to cats, the contents of one bottle are dissolved in 3.6 ml of 0.25%-0.5% novocaine solution or sterile water for injection. When used in cats, the drug should not be diluted with lidocaine. 1 ml of the prepared solution contains approximately 250 mg of ceftriaxone.

For intravenous administration, the contents of the vial are dissolved in 9.6 ml of sterile water for injection or 0.9% sodium chloride solution or 5% glucose solution. 1 ml of the prepared solution contains approximately 100 mg of ceftriaxone.

For intravenous drip, the contents of the bottle are dissolved in 100-250 ml of 0.9% sodium chloride solution or 5% glucose solution. The infusion of the prepared solution is carried out for 20-30 minutes at an injection rate of 60-80 drops per minute.
The daily dose of the drug is 20-40 mg of ceftriaxone per 1 kg of animal body weight. If necessary, the frequency of use can be increased to 2 times a day at a dose of 10-20 mg of ceftriaxone per 1 kg of animal body weight. The course of taking the drug is 5-10 days, depending on the severity and course of the disease. ⚠ Contraindication:
Increased individual sensitivity to drugs from the cephalosporin group and other beta-lactam antibiotics; renal or hepatic failure; pregnancy
⚠ Precautions when using:
When treating dogs with high doses of ceftriaxone, stones may form in the gallbladder. With increased sensitivity to lidocaine, it is not recommended to use its 1% solution as a solvent. 🟢 Composition of the drug:
1 vial contains the active substance:
ceftriaxone sodium salt - 1.0 g.
Pharmacological properties:
Ceftriaxone is an antibiotic from the beta-lactam group, a third-generation cephalosporin with bactericidal action. The mechanism of action of the drug is associated with the inhibition of the activity of the enzyme transpeptidase, disruption of the biosynthesis of the peptidoglycan of the cell wall of microorganisms. The drug has a wide range of action: active against Gram-positive aerobic bacteria: Staphylococcus aureus (including strains producing penicillinase), Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus viridans; Gram-negative aerobes: Enterobacter aerogenes, Enterobacter cloacae, Escherichia coli, Haemophilus influenzae, Haemophilusparainfluenzae, Klebsiella spp. (including K. pneumoniae), Moraxella catarrhalis, Morganella morganii, Neisseria gonorrhoeae, N. meningitidis, Proteus mirabilis, Proteus vulgaris, Serratia spp. (including Serratia marcescens), Acinetobacter calcoaceticus, Pseudomonas aeruginosa; obligate anaerobes: Bacteroides fragilis, Peptostreptococcus spp., Clostridium spp. (except Clostridium difficile). It also acts on most strains of microorganisms: Providenda spp., Bacteroides bivius, Bacteroides melaninogenicus, Salmonella spp. (including Salmonella typhi), Shigella spp., Streptococcus agaladiae, Providenda rettgeri, Citrobacter freundii. The drug is prescribed for resistance of microflora to other drugs from the cephalosporin series, aminoglycosides, penicillins, etc. After intramuscular administration, the drug is absorbed quickly and completely. The bioavailability of the substance is about 100%.

Storage
A dry, dark place inaccessible to children at a temperature of 15 ° C to 25 ° C.

⚠ Store the prepared solution for no longer than 6 hours at a temperature not higher than 25 ° C and no longer than 24 hours at a temperature of 2 to 8 ° C.

The shelf life is 3 years from the date of production.