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Pharmacological properties
Gentamicin is a bactericidal antibiotic of the aminoglycoside group, which is a mixture of gentamicin components C1, C2 and C1a, similar in chemical structure. The mechanism of bactericidal action of gentamicin is based on the disorder of protein biosynthesis in bacterial ribosomes due to interaction with mRNA and subsequent inhibition of translation. Gentamicin sensitivity is generally confirmed for the following microorganisms: aerobic gram-positive microorganisms - Bacillus spp., Corynebacterium spp., Staphylococcus aureus (methicillin-sensitive strains); aerobic gram-negative microorganisms: Acinetobacter baumannii, Acinetobacter lwoffii, Haemophilus influenzae, Haemophilus parainfluenzae, Enterobacter cloacae, Escherichia coli, Klebsiella oxytoca, Klebsia as aeruginosa, Serratia marcescens. Dexamethasone is a monofluorocorticosteroid with pronounced anti-allergic, anti-inflammatory and membrane-stabilizing properties, which also affects the metabolism of carbohydrates, proteins and lipids. The anti-inflammatory, immunosuppressive, and antiproliferative effects of corticosteroids are partially due to a reduction in the formation, release, and activity of inflammatory mediators and inhibition of specific functions and migration of cells involved in the inflammatory process.
Recommendations for use
It is used to treat cats and dogs with infectious and inflammatory diseases of the eyes and nose caused by microorganisms sensitive to gentamicin. For allergic processes of the front part of the eye, complicated by bacterial infection, as well as for the purpose of prevention and treatment of inflammatory phenomena in the postoperative period. Instilled into the conjunctival sac
or
1-2 drops in the nostril 4-6 times a day. The duration of treatment usually does not exceed 2-3 weeks. Hypersensitivity to the components of the drug.
Special instructions:
No special measures are foreseen.
Side effect
On the part of the organs of vision: allergic reactions in the form of burning rarely occur after using the drug. With long-term use - the development of secondary glaucoma, steroid cataract.
Caution for service personnel
You should follow generally accepted rules of personal hygiene and safety techniques, which are provided for when working with eye drops. Unused product or its residues must be disposed of in accordance with current requirements.
Expiration date
The shelf life is 24 months from the date of manufacture. Use within 14 days after opening the bottle.
Release form
Vials of 10 ml.
Conditions of storage and transportation
Store in a dry, dark place at a temperature of 0°C to 20°C for 24 months. Not subject to freezing