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COMPOSITION:
1 ml of the preparation contains the active substance:
sodium nucleinate 1 mg.
Excipients: complex of biologically active substances, methylparaben, propylparaben, propylene glycol, water for injection.
* Complex of biologically active substances contains:
VITAMINS AND VITAMIN-LIKE SUBSTANCES — D-biotin, ergocalciferol, choline chloride, folic acid, menadione, myo-inositol, niacinamide, nicotinic acid, hydropinotidoide, D-biotinol acetate, riboflavin, α-tocopherol phosphate, thiamine hydrochloride;
AMINO ACIDS - L-alanine, L-arginine hydrochloride, aspartic acid, L-cysteine, L-cystine, L-glutamine, glutamic acid, glycine, L-histidine, L-isoleucine, L-leucine, L-lysine, L-methionine, L-phenylalanine, L-proline, L-serine, L-threonine, L-tryptophan, L-tyrosine, L-valine, adenine hemisulfate, adenine, adenosine, hydroxyproline;
MINERAL SUBSTANCES - calcium chloride, iron nitrate, magnesium sulfate, potassium chloride, sodium acetate, sodium chloride, sodium monobasic phosphate;
OTHER, INCLUDING BIOLOGICAL ACTIVE COMPONENTS - deoxyribose, ribose, glucose, cholesterol, glutathione, hypoxanthine, phenol red, tween-80, thymine, uracil, xanthine.
PHARMACOLOGICAL PROPERTIES
The drug has an adaptogenic, immunostimulating, general tonic effect; improves metabolism, cellular metabolism, tissue regeneration due to the presence of sodium nucleinate and a balanced complex of minerals, amino acids and vitamins in the drug.
Sodium nucleinate is an inducer of leukocyte reaction, a stimulator of intracellular metabolism, nucleic acid metabolism, especially in case of immunodeficiency in the body of animals. It has anti-inflammatory activity, suppresses increased platelet aggregation.
The following mechanisms underlie the pharmacotherapeutic effects: stimulation of cellular metabolism processes, increased biosynthesis of endogenous nucleic acids, specific proteins and enzymes; increased mitotic activity of bone marrow cells, acceleration of regeneration processes; increased energy supply to the cell by stimulating the synthesis of macroergic compounds such as ATP; normalization of NO synthase activity, inhibition of oxidative processes in cell membranes, stabilization of cell membranes and optimization of oxidation-reduction processes in tissues; increased production of interferon and stimulation of antiviral protection; activation of the pituitary-adrenal-glandular system with an increase in the level of endogenous glucocorticoids.
APPLICATION
The drug is used as a tonic in a complex of therapeutic measures in the treatment of cattle, horses, pigs, fur animals, dogs, cats, and poultry. It is used for anemia, hypovitaminosis, infectious and invasive diseases, diseases of the reproductive system, to stimulate hunting, as well as poisoning, in the postoperative period; as a general tonic for preventive purposes in preparing animals for exhibitions, competitions and transportation.
It is used for young animals to enhance growth and improve development; other categories of exhausted and weakened animals.
DOSAGE
The drug is administered subcutaneously, intramuscularly, intravenously.
Oral use with drinking water is possible.
TABLE 1. DOSAGE FOR MEDICINAL PURPOSES
INTENDED USE
METHOD OF ADMINISTRATION
DOSAGE, ML/KG OF BODY MASS
TREATMENT COURSE
Treatment of animals, in a complex of therapeutic approaches for hypovitaminosis, infectious and parasitic diseases, after surgeries
Internally
0.3-0.5
1-3 times per day, 5-10 days
Internally
0.15-0.25
Orally (on the root of the tongue).
For convenience, the dose of the drug can be mixed with a small amount of drinking water.
0.6-1.0
When cutting, in a complex of therapeutic approaches
Intravenously, by jet stream or droplet, subcutaneously
1.0-1.5
Two times a day,
5-10 days
TABLE 2. DOSAGE FOR PREVENTIVE USE
PURPOSE
ADMINISTRATION COURSE
METHOD OF ADMINISTRATION, DOSAGE, ML/KG BODY WEIGHT
In stimulating schemes for hunting, to increase fertility of female farm animals
A few years before autumn
Skin, internally
at a dose of 0.05 ml
For the prevention of post-natal complications (afterbirth retention, metritis) in a complex of approaches
Twice, before bedtime, and again in 7 days.
For better fetal development
1-3 times per month in the first half of pregnancy
For females to prevent metabolic disorders and reduce body weight loss during lactation
1-3 times per month during the lactation period
To increase weight gain at maturity
At the beginning of maturity, once per day, on the 1st, 4th and 9th days
Intravenously,
in a dose of 0.1 ml
To increase the preservation of young animals, natural resistance and immunity
Once per day, on the 1st, 3rd, 5th, 7th and 21st day of life
For young and adult animals during periods of intensive loading, during transportation, overloading, dietary changes and other stresses
1-3 times per week, if necessary, in a course of 8; 6 t
and 4 times before the injection of the pre-treated stress factor
For deworming of small animals
One-time, in the complex therapy
Subcutaneously, internally
0.3-0.5 ml
For violation of the norm of deworming of small animals
Once per day, for 5-7 days
For deworming of small animals and in the post-vaccination period
Twice, immediately before and 24 hours after treatment
For treatment of small animals in obstetric and gynecological diseases
Once per day, for 5-7 days
For laying hens to increase laying rate and increase egg mass
Working rate fill the waterer with the amount of 2-year-old water consumption.
They are drunk for 2 hours, once a day, 4-5 days after. Before administering the drug, the bird is kept without water for 1 year.
Orally with drinking water, 5 ml/l of water
For the preservation of healthy chickens
For increasing body weight gain in broiler chickens
Incompatibility with other drugs, feed and feed additives is unknown.
SIDE EFFECTS:
None.
WARNING:
None.
RELEASE FORM:
Vials made of glass or polymeric materials of 10, 50, 100, 200, 250 ml.
STORAGE:
A dark place inaccessible to children at a temperature of 2 to 8 ° C.
Shelf life is 1 year.
After the first selection from the vial - 7 days when stored in a dry, dark place at a temperature of 2 to 8 ° C.