Storage
1 ml of suspension contains (active substances):

tobramycin - 3.0 mg;
dexamethasone - 1.0 mg;
Auxiliary substances: benzalkonium chloride, disodium edetate, sodium chloride, anhydrous sodium sulfate, tiloxapol, hydroxyethyl cellulose, sulfuric acid and / or sodium hydroxide, water for injections.

Contraindication
hypersensitivity to the active substances or to any component of the medicinal product;
keratitis caused by herpes simplex virus;
cowpox, chickenpox and other viral infections of the cornea and conjunctiva;
fungal diseases of the structures of the eye or treated parasitic infections of the eye;
mycobacterial eye infections.
Application method
For ophthalmic use.

Adults, including elderly patients, and children from 12 to 18 years old
Instill one or two drops into the conjunctival sac(s) every 4-6 hours. During the first 24-48 hours, the dose can be increased to one or two drops every 2 hours. The frequency of use of the medicinal product should be gradually reduced when clinical signs improve.

Care should be taken not to stop therapy prematurely.

In severe diseases, instill one or two drops every hour until the inflammation becomes controlled, and gradually reduce the frequency of use to one or two drops every 2 hours for 3 days; after that, bury 1-2 drops every 4 hours for 5-8 days and at the end - 1-2 drops every day for the last 5-8 days if necessary.

After cataract surgery, the dose is one drop 4 times a day, starting from the day of surgery and continuing for 24 days. Treatment can be started the day before the operation with one drop 4 times a day, continuing to instill one drop after the operation, and then 4 times a day for 23 days. If necessary, the frequency of use of the drug can be increased to one drop every 2 hours during the first two days of therapy.

It is recommended to constantly monitor the intraocular pressure.

It is recommended to press on the area of ​​the nasolacrimal opening and carefully close the eyelids after instillation. This reduces the systemic absorption of drugs injected into the eye, which reduces the likelihood of systemic side effects.

Application to children
The obtained data confirm the safety and effectiveness of the use of the drug in children from the age of 1, who were treated with the drug for 7 days for the treatment of superficial inflammation of the eye of bacterial origin.

It can be used for children who need surgery to remove cataracts.

Method of use
Shake the bottle well before use.

To prevent contamination of the edge of the dropper and the contents of the bottle, it is necessary to be careful and not to touch the eyelids, adjacent areas and other surfaces with the edge of the dropper bottle.

Store the bottle in an upright position.

Features of application
pregnant
It is not recommended to use the drug "Tobiflamin" during pregnancy.

Since many drugs pass into breast milk, the possibility of temporarily stopping breastfeeding while using the drug should be considered.

Drivers
This drug does not affect or has a minor effect on the ability to drive vehicles or other mechanisms. Temporary blurring of vision or other visual impairments may affect the ability to drive or operate machinery. If blurred vision occurs during instillation, the patient must wait until vision clears before driving or operating machinery.

Overdose
Given the characteristics of this medicinal product intended for local use, no toxic effect is expected both when it is used in ophthalmology in the recommended doses and when accidentally swallowing the contents of the bottle. Possible clinical signs and symptoms of drug overdose (punctate keratitis, erythema, increased lacrimation, swelling and itching of the eyelids) may be similar side effects observed in some patients.

In case of an overdose with the drug "Tobiflamin" when used topically, wash the excess of the drug from the eye(s) with warm water.

Side effects
The most common adverse reactions, occurring in less than 1% of patients, were eye pain, increased intraocular pressure, eye irritation, and eye itching.

Storage conditions
Store in the original packaging at a temperature not higher than 25 °C, in a place inaccessible to children.

Shelf life - 2 years.

After opening the bottle, the shelf life is no more than 4 weeks.